Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.31 |
| ▸ | CPT1A | P50416 | 2/20 | 0.31 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586627 | 0.86 | CYP11B1 (0.41) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL30695802 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL3068531 | 0.79 | AHR (0.56) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL3597266 | 0.79 | LMNA (0.51) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL434348 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL787497 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL31261247 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL10916724 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL13692913 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 | |
| SCHEMBL4395266 | 0.76 | CYP11B1 (0.46) | CYP11B1CYP11B2PDE3BPDE3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | CYP11B1 162/4885CYP11B2 165/4885PDE3B 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.