SCHEMBL3598429

SCHEMBL3598429

[O]C(=O)C1C/C=C/CCCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
ALDH1A1 P00352 3/20 0.34
TSHR P16473 2/20 0.34
HSD11B1 P28845 4/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
HTT P42858 1/20 0.34
ESR2 Q92731 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTPN1 P18031 1/20 0.32
HPGD P15428 1/20 0.32
HSD11B2 P80365 1/20 0.31
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3598427 1.00 CES2 (0.41) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL3598433 0.83 CES2 (0.41) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL28247066 0.83 CES2 (0.41) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL27620323 0.82
Benzene SCHEMBL30877908 0.82 ALDH1A1 (0.40) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL23113665 0.81 ABAT (0.39) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL22975387 0.81 ABAT (0.39) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL621701 0.79 CES2 (0.36) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL621700 0.79 CES2 (0.36) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL30754357 0.79 CES2 (0.36) CES2CES1HDAC8HDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11724243-B2 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. (US) 2023-08-15 US disclosed
US-20210395906-A1 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY CUSTOMARRAY INC (US) 2021-12-23 US disclosed
US-10724143-B1 Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array CUSTOMARRAY, INC. (US) 2020-07-28 US disclosed
US-20190255504-A1 Electrode Array Device Having an Adsorbed Porous Reaction Layer CUSTOMARRAY, INC. (US) 2019-08-22 US disclosed
EP-3521485-A1 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY CustomArray,Inc. (US) 2019-08-07 EP disclosed
EP-3517236-A1 ELECTRODE ARRAY DEVICE HAVING AN ADSORBED POROUS REACTION LAYER CustomArray,Inc. (US) 2019-07-31 EP disclosed
US-20190227060-A1 MICROARRAY HAVING A BASE CLEAVABLE LINKER CUSTOMARRAY, INC. (US) 2019-07-25 US disclosed
EP-1869061-B1 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY CUSTOMARRAY INC (US) 2019-05-22 EP disclosed
US-10286377-B1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. (US) 2019-05-14 US disclosed
US-10261075-B2 Microarray having a base cleavable linker CUSTOMARRAY, INC. (US) 2019-04-16 US disclosed
WO-2007035500-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCCINATE LINKER COMBIMATRIX CORPORATION (US) 2007-03-29 WO disclosed
US-20070065877-A1 Microarray having a base cleavable succinate linker COMBIMATRIX CORPORATION 2007-03-22 US disclosed
US-20070034513-A1 Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array COMBIMATRIX CORPORATION 2007-02-15 US disclosed
WO-2006105037-A2 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY COMBIMATRIX CORPORATION (US) 2006-10-05 WO disclosed
WO-2006055943-A2 ELECTRODE ARRAY DEVICE HAVING AN ADSORBED POROUS REACTION LAYER HAVING A LINKER MOIETY COMBIMATRIX CORPORATION (US) 2006-05-26 WO disclosed
WO-2006055810-A2 ELECTRODE ARRAY DEVICE HAVING AN ADSORBED POROUS REACTION LAYER COMBIMATRIX CORPORATION (US) 2006-05-26 WO disclosed
US-20060105355-A1 Electrode array device having an adsorbed porous reaction layer having a linker moiety KARL MAURER 2006-05-18 US disclosed
US-20060102471-A1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. 2006-05-18 US disclosed
WO-2006031814-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE COMBIMATRIX CORPORATION (US) 2006-03-23 WO disclosed
US-20060054511-A1 Electrochemical deblocking using a hydrazine derivative CUSTOMARRAY, INC. 2006-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395906-A1 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY DNMT1, DNASE1, DNPEP CES2 1453/4885CES1 4376/4885HDAC8 2995/4885
US-10724143-B1 Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array DNMT1, DNASE1, DNPEP CES2 1453/4885CES1 4376/4885HDAC8 2995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.