Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608317 | 0.84 | NMT1 (0.33) | — | |
| SCHEMBL3610875 | 0.83 | PDE10A (0.31) | — | |
| SCHEMBL3618679 | 0.79 | TSHR (0.37) | ALDH1A1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL3606741 | 0.79 | POLB (0.45) | — | |
| SCHEMBL3612535 | 0.74 | — | — | |
| SCHEMBL3605018 | 0.72 | PDE10A (0.33) | — | |
| SCHEMBL12806867 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL3616664 | 0.69 | SHMT2 (0.33) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL13242970 | 0.69 | ALDH1A1 (0.45) | ALDH1A1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL3613260 | 0.69 | PDE10A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016396-A1 | PYRAZOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128138-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016396-A1 | PYRAZOLE COMPOUND | SLC5A1, SLC5A2, GLP1R | ALDH1A1 365/4885KMT2A 2269/4885KDM4E 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.