SCHEMBL3598869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3598763	0.90	PDE9A (0.57)	PDE9APDE10APOLBMEN1KMT2A
	SCHEMBL3591867	0.89	PDE9A (0.56)	PDE9APDE10APOLBMEN1KMT2A
	SCHEMBL3598268	0.83	PDE9A (0.74)	PDE9APOLBPDE5APDE1APDE1B
	SCHEMBL3491843	0.83	PDE9A (1.00)	PDE9APOLBMEN1KMT2APDE5A
	SCHEMBL3592062	0.83	PDE9A (0.55)	PDE9AMEN1KMT2AALDH1A1KDM4E
	SCHEMBL13503466	0.83	PDE9A (0.55)	PDE9AMEN1KMT2AALDH1A1KDM4E
	SCHEMBL3596674	0.81	PDE9A (0.54)	PDE9APDE10AMEN1KMT2APDE5A
	SCHEMBL3585751	0.80	PDE9A (0.93)	PDE9APOLBMEN1KMT2APDE5A
	SCHEMBL3598874	0.79	PDE9A (0.50)	PDE9APDE10AMEN1KMT2APDE5A
	SCHEMBL3596495	0.78	PDE9A (0.51)	PDE9APDE10AMEN1KMT2APDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.