Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13547014 | 0.92 | PPARA (0.47) | PPARAPPARGL3MBTL1IKBKBFNTA | |
| SCHEMBL3605095 | 0.87 | PPARA (0.45) | PPARAPPARGL3MBTL1ALDH1A1 | |
| SCHEMBL3609694 | 0.87 | PPARA (0.55) | PPARAPPARGL3MBTL1KDM4E | |
| SCHEMBL3619631 | 0.85 | DGAT1 (0.48) | PPARAPPARGL3MBTL1 | |
| SCHEMBL3615928 | 0.85 | PPARG (0.40) | PPARAPPARGL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL14219122 | 0.84 | PPARA (0.47) | PPARAPPARGL3MBTL1 | |
| SCHEMBL3604902 | 0.81 | PPARA (0.49) | PPARAPPARGL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3832671 | 0.81 | PPARG (0.41) | PPARAPPARGL3MBTL1IKBKBFNTA | |
| SCHEMBL3619637 | 0.81 | PPARA (0.49) | PPARAPPARGL3MBTL1IKBKBALDH1A1 | |
| SCHEMBL3623449 | 0.81 | PPARA (0.49) | PPARAPPARGL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2010-03-25 | — | — | US | disclosed |
| US-20100022541-A1 | Chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors | MUTABILIS SA (FR) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022541-A1 | Chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors | CBR1, OXER1, CBR3 | PPARA 2162/4885PPARG 1817/4885L3MBTL1 2972/4885 |
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | MIF, IMPDH1, IMPDH2 | PPARA 4363/4885PPARG 4457/4885L3MBTL1 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.