Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257404 | 0.80 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3588993 | 0.77 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8687546 | 0.77 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8828087 | 0.77 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3598675 | 0.77 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8746891 | 0.75 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3599325 | 0.75 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL32661827 | 0.75 | DAO (0.63) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL31154578 | 0.75 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL6402311 | 0.73 | DAO (0.59) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
| CN-101589038-A | Heterocyclidene-N-(aryl)acetamide derivative | MOCHIDA PHARM CO LTD (JP) | 2009-11-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | GRIA1 1858/4885GRIA2 2053/4885GRIA3 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.