Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.60 |
| ▸ | PARP1 | P09874 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20267527 | 0.87 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL29533215 | 0.87 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL4969287 | 0.81 | MAPT (0.51) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL7257404 | 0.81 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3598675 | 0.77 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8828087 | 0.77 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3600441 | 0.77 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8687546 | 0.77 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL4427396 | 0.76 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8746891 | 0.76 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
| CN-101589038-A | Heterocyclidene-N-(aryl)acetamide derivative | MOCHIDA PHARM CO LTD (JP) | 2009-11-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | GRIA1 1858/4885GRIA2 2053/4885GRIA3 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.