Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741263 | 0.80 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL7257404 | 0.80 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3588993 | 0.77 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3598675 | 0.77 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL3600441 | 0.77 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8687546 | 0.77 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL7734991 | 0.76 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3203267 | 0.74 | DAO (0.58) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4427396 | 0.73 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8746891 | 0.72 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |