Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600450 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTKCNH2SCN3ATSHR | |
| SCHEMBL28521573 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTKCNH2SCN3ATSHR | |
| SCHEMBL21094112 | 0.86 | KCNH2 (0.46) | ALDH1A1MAPTKCNH2TSHRPKM | |
| SCHEMBL2346176 | 0.86 | MEN1 (0.47) | ALDH1A1MAPTKCNH2SCN3ATSHR | |
| SCHEMBL2350627 | 0.86 | KCNH2 (0.56) | ALDH1A1KCNH2SCN3AMEN1CYP1A2 | |
| SCHEMBL3585037 | 0.86 | KCNH2 (0.56) | ALDH1A1KCNH2SCN3AMEN1CYP1A2 | |
| SCHEMBL4637526 | 0.86 | KCNH2 (0.56) | ALDH1A1KCNH2SCN3AMEN1CYP1A2 | |
| SCHEMBL3585032 | 0.86 | KCNH2 (0.56) | ALDH1A1KCNH2SCN3AMEN1CYP1A2 | |
| SCHEMBL4637528 | 0.86 | KCNH2 (0.56) | ALDH1A1KCNH2SCN3AMEN1CYP1A2 | |
| SCHEMBL13311587 | 0.85 | KCNH2 (0.71) | MAPTKCNH2SCN3ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063065-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LIMITED (GB) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063065-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | PPARG, PPARD, PPARA | ALDH1A1 1049/4885MAPT 4061/4885KCNH2 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.