Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835748 | 0.87 | KCNH2 (0.49) | KCNH2ALDH1A1MAPTPKM | |
| SCHEMBL21094085 | 0.87 | KCNH2 (0.44) | KCNH2ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL24220439 | 0.87 | KCNH2 (0.49) | KCNH2ALDH1A1MAPTPKM | |
| SCHEMBL28521573 | 0.86 | ALDH1A1 (0.51) | KCNH2ALDH1A1MAPTPKMTSHR | |
| SCHEMBL3600447 | 0.86 | ALDH1A1 (0.51) | KCNH2ALDH1A1MAPTPKMTSHR | |
| SCHEMBL3600450 | 0.86 | ALDH1A1 (0.51) | KCNH2ALDH1A1MAPTPKMTSHR | |
| SCHEMBL20835449 | 0.82 | KCNH2 (0.51) | KCNH2ALDH1A1MAPTKMT2AHTR2C | |
| SCHEMBL8871030 | 0.82 | KCNH2 (0.51) | KCNH2ALDH1A1MAPTKMT2AHTR2C | |
| SCHEMBL8871025 | 0.82 | KCNH2 (0.51) | KCNH2ALDH1A1MAPTKMT2AHTR2C | |
| SCHEMBL31369670 | 0.82 | KCNH2 (0.51) | KCNH2ALDH1A1MAPTKMT2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |