Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12269117 | 0.81 | HRH4 (0.35) | HDAC6RAB9ANPC1SCN4ASMN1; SMN2 | |
| SCHEMBL19341416 | 0.76 | KMT2A (0.34) | KMT2ASMN1; SMN2KCNH2ALDH1A1 | |
| SCHEMBL368876 | 0.73 | KMT2A (0.33) | KMT2A | |
| SCHEMBL360056 | 0.73 | KMT2A (0.33) | KMT2A | |
| SCHEMBL359349 | 0.73 | DYRK1A (0.36) | KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL21206606 | 0.72 | AADAT (0.36) | KMT2ARAB9ANPC1SCN4ASMN1; SMN2 | |
| SCHEMBL22758276 | 0.69 | PIK3CD (0.32) | KCNH2HRH4HRH3 | |
| SCHEMBL20685684 | 0.69 | GRM5 (0.34) | KMT2A | |
| SCHEMBL31456669 | 0.69 | KMT2A (0.34) | KMT2A | |
| SCHEMBL21481142 | 0.68 | KCNH2 (0.30) | KCNH2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |