Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 7/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472326 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL360736 | 0.77 | HTT (0.41) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL368903 | 0.77 | AXL (0.46) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL360056 | 0.77 | KMT2A (0.33) | IDO1 | |
| SCHEMBL19329221 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL12724429 | 0.73 | — | — | |
| SCHEMBL12702002 | 0.69 | ACACB (0.34) | PI4KAPI4KBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL31456648 | 0.69 | CYP3A4 (0.37) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL9072335 | 0.68 | EGFR (0.37) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL30858956 | 0.68 | EGFR (0.37) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |