⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607261 | 0.86 | — | — | |
| SCHEMBL3601976 | 0.80 | KMT2A (0.41) | — | |
| SCHEMBL3597065 | 0.78 | EPAS1 (0.41) | — | |
| SCHEMBL3600890 | 0.75 | GCK (0.42) | — | |
| SCHEMBL3607258 | 0.73 | GCK (0.34) | — | |
| SCHEMBL13577642 | 0.70 | DHFR (0.38) | — | |
| SCHEMBL3592401 | 0.68 | KMT2A (0.42) | — | |
| SCHEMBL16037175 | 0.67 | NPC1 (0.39) | — | |
| SCHEMBL28926462 | 0.67 | KDM4C (0.39) | — | |
| SCHEMBL26129077 | 0.65 | PGR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700640-B2 | Process for making phenoxy benzamide compounds | ASTRAZENECA AB (SE) | 2010-04-20 | — | — | US | disclosed |
| US-20080200694-A1 | Process for Making Phenoxy Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | US | disclosed |
| EP-1802570-A1 | PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS | AstraZeneca AB (SE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040527-A1 | PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |