Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7944630 | 0.98 | CYP2C9 (0.53) | CYP2C9CYP2C19CHRNB2CHRNB4CHRNA3 | |
| Phosphoric Acid SCHEMBL27561421 | 0.92 | CYP2C9 (0.47) | CYP2C9CYP2C19CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11870125 | 0.89 | CYP2C9 (0.46) | CYP2C9CYP2C19CHRNB2CHRNB4CHRNA3 | |
| Bicarbonate SCHEMBL8928177 | 0.88 | THRB (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CA12 | |
| Formaldehyde SCHEMBL4291618 | 0.88 | CA12 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CA12 | |
| SCHEMBL88417 | 0.88 | AOC3 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CA12 | |
| SCHEMBL16371575 | 0.88 | AOC3 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CA12 | |
| Phosphoric Acid SCHEMBL28106043 | 0.87 | CA12 (0.50) | CYP2C9CYP2C19CHRNB2CHRNB4CHRNA3 | |
| Phosphoric Acid SCHEMBL27892061 | 0.86 | AOC3 (0.51) | CYP2C9CYP2C19CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3744653 | 0.86 | CA12 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111033821-B | Positive electrode for nonaqueous electrolyte secondary battery and nonaqueous electrolyte secondary battery | 松下知识产权经营株式会社 | 2023-06-16 | — | — | CN | claimed |
| CN-111690152-B | Rubber modified asphalt latex and preparation method and application thereof | 中铁四局集团有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-111253515-B | Aqueous dispersion | 第一工业制药株式会社 | 2022-11-25 | — | — | CN | claimed |
| US-11462726-B2 | Positive electrode for nonaqueous electrolyte secondary batteries, and nonaqueous electrolyte secondary battery | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2022-10-04 | — | — | US | claimed |
| CN-111690152-A | Rubber modified asphalt latex and preparation method and application thereof | 中铁四局集团有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-110352967-A | A kind of composition, preparation and its application, preparation method | 东莞东阳光科研发有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-109964940-A | A kind of application of miticide composition and its preparation, miticide composition and preparation | 东莞东阳光科研发有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109963466-A | The method for managing herbicide evaporation | 阿格夸姆公司 | 2019-07-02 | — | — | CN | claimed |
| CN-108949133-A | Foam flooding system and preparation method thereof | 中国石油化工股份有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-104725549-B | High-performance nano composite emulsion | 长兴化学工业(中国)有限公司 | 2018-09-04 | — | — | CN | claimed |
| US-20080060551-A1 | METHOD FOR PRODUCING BITUMEN COMPOSITIONS | JPMORGAN CHASE BANK, N.A. | 2008-03-13 | — | — | US | claimed |
| WO-2007126922-A1 | SKIN CLEANSER | PHILLIPS DOUGLAS HOWARD (US) | 2007-11-08 | — | — | WO | claimed |
| US-20070232694-A1 | SKIN CLEANSER | PHILLIPS DOUGLAS H | 2007-10-04 | — | — | US | claimed |
| WO-2007112335-A2 | WATER-IN-OIL BITUMEN DISPERSIONS AND METHODS FOR PRODUCING PAVING COMPOSITIONS FROM THE SAME | MEADWESTVACO CORPORATION (US) | 2007-10-04 | — | — | WO | claimed |
| US-7188630-B2 | Method to passivate conductive surfaces during semiconductor processing | FREESCALE SEMICONDUCTOR, INC. (US) | 2007-03-13 | — | — | US | claimed |
| US-20040224521-A1 | Method to passivate conductive surfaces during semiconductor processing | NXP, B.V. F/K/A FREESCALE SEMICONDUCTOR, INC. (NL) | 2004-11-11 | — | — | US | claimed |
| US-6277910-B1 | OBTAINED BY MIXING AN AQUEOUS DISPERSION A OF A POLYMER OF GIVEN DRY SOLIDS CONTENT, SURFACTANT(S) AND EMULSIFIABLE RESIN(S) WHICH IS ADDED TO DISPERSION A UNDER AGITATION; HIGH SOLIDS CONTENT; USE AS PAINT OR LACQUER | AKZO NOBEL INDUSTRIAL COATINGS, AB (SE) | 2001-08-21 | — | — | US | claimed |
| EP-0874875-B1 | WATER-BORNE HYBRID BINDER COMPOSITION AND USE THEREOF | AKZO NOBEL IND COATINGS AB (SE) | 2001-06-13 | — | — | EP | claimed |
| EP-0874875-A1 | WATER-BORNE HYBRID BINDER COMPOSITION AND USE THEREOF | Akzo Nobel Industrial Coatings AB (SE) | 1998-11-04 | — | — | EP | claimed |
| WO-1997026303-A1 | WATER-BORNE HYBRID BINDER COMPOSITION AND USE THEREOF | AKZO NOBEL INDUSTRIAL COATINGS AB (SE) | 1997-07-24 | — | — | WO | claimed |