Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598377 | 0.91 | DPP4 (0.43) | DPP4SIGMAR1DPP8TGFBR1HTT | |
| SCHEMBL3598863 | 0.90 | HTT (0.43) | DPP4SIGMAR1DPP8HTTKMT2A | |
| SCHEMBL3600930 | 0.81 | DPP4 (0.46) | DPP4DPP8 | |
| SCHEMBL3091767 | 0.81 | DPP4 (0.50) | DPP4DPP8 | |
| SCHEMBL3600855 | 0.80 | DPP4 (0.45) | DPP4DPP8 | |
| SCHEMBL3096850 | 0.79 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL3596892 | 0.79 | DPP4 (0.44) | DPP4DPP8TGFBR1 | |
| SCHEMBL3600802 | 0.79 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL3596963 | 0.78 | DPP4 (0.58) | DPP4DPP8 | |
| SCHEMBL4660649 | 0.78 | DPP4 (0.48) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |