SCHEMBL360198

SCHEMBL360198

[NH]CC(O)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4424181 1.00
SCHEMBL588616 1.00
SCHEMBL7131084 0.81
SCHEMBL6735503 0.79
Glycerin SCHEMBL8080917 0.74 LMNA (1.00)
Glycerin SCHEMBL14278797 0.74
Glycerin SCHEMBL9439059 0.74 LMNA (1.00)
Glycerin SCHEMBL3418854 0.74 LMNA (1.00)
Glycerin SCHEMBL10453101 0.74 LMNA (1.00)
Glycerin SCHEMBL797 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023139242-A1 METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF INSTITUT PASTEUR (FR) 2023-07-27 WO claimed
CN-115155529-A Boron adsorption resin and preparation method thereof 南开大学 2022-10-11 CN claimed
EP-3666767-B1 PHTHALAZINONE DERIVATIVES, METHOD FOR THEIR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING THEM, AND THEIR USE SHANGHAI INST MATERIA MEDICA CAS (CN) 2021-12-01 EP claimed
US-11040952-B2 Phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2021-06-22 US claimed
CN-109134429-B Phthalazinone compound, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2021-06-01 CN claimed
EP-3666767-A1 PYRIDAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2020-06-17 EP claimed
US-20200181109-A1 PHTHALAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2020-06-11 US claimed
EP-3294741-B1 5-SUBSTITUTED 7-[4-(2-PYRIDYL)PHENYLMETHYLAMINO]-3-ISO PROPYLPYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES, USE THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS USTAV EXPERIMENTALNI BOTANIKY AV CR V V I (CZ) 2019-05-01 EP claimed
CN-109134429-A Phthalazines ketone compounds, preparation method, pharmaceutical composition and purposes 中国科学院上海药物研究所 2019-01-04 CN claimed
US-20180298026-A1 Pyrazolo[1,5a]Pyrimidine Derivatives as IRAK4 Modulators HOFFMANN-LA ROCHE INC. 2018-10-18 US claimed
US-4866163-A DYEING AND PRINTING OF HYDROXY GROUP OR NITROGEN CONTAINING ORGANIC SUBSTRATES; COLORFASTNESS SANDOZ, LTD. (CH) 1989-09-12 US claimed
EP-0329295-A1 Renin inhibiting peptides with polar end groups THE UPJOHN COMPANY (US) 1989-08-23 EP claimed
WO-1989007109-A1 RENIN INHIBITING PEPTIDES WITH POLAR END GROUPS THE UPJOHN COMPANY (US) 1989-08-10 WO claimed
EP-0164247-B1 DIHYDROPYRIDINES Pfizer Limited (GB) 1989-01-11 EP claimed
US-4722951-A BLEND WITH POLYSILOXANE-NONPEELING SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-02-02 US claimed
US-4618609-A Anti-ischaemic and antihypertensive 2-[pyrimidyloxy alhoxymethyl]-1,4-dihydropyridines PFIZER INC. (US) 1986-10-21 US claimed
EP-0164247-A1 Dihydropyridines Pfizer Limited (GB) 1985-12-11 EP claimed
US-4555247-A MIXTURE OF VIOLET AND YELLOW DYESTUFFS L'OREAL (FR) 1985-11-26 US claimed
US-4189550-A HYDROXYALKYL AMINE COMPOUNDS AND SALTS DEUTSCHE GOLD- UND SILBER-SCHEINDEANSTALT VORMALS ROESSLER (DE) 1980-02-19 US claimed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP claimed