⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775621 | 0.77 | — | — | |
| SCHEMBL1446243 | 0.71 | — | — | |
| SCHEMBL4429690 | 0.70 | — | — | |
| SCHEMBL302005 | 0.70 | — | — | |
| SCHEMBL3809774 | 0.69 | — | — | |
| SCHEMBL10487376 | 0.69 | — | — | |
| SCHEMBL5603642 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL8122291 | 0.68 | — | — | |
| SCHEMBL2310348 | 0.67 | — | — | |
| SCHEMBL6121856 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075966-A1 | Substituted Dihydroimidazoles and their Use in the Treatment of Tumors | NOVARTIS AG | 2010-03-25 | — | — | US | claimed |
| EP-2097386-A2 | SUBSTITUTED DIHYDROIMIDAZOLES AND THEIR USE IN THE TREATMENT OF TUMORS | Novartis AG (CH) | 2009-09-09 | — | — | EP | claimed |
| WO-2008065068-A2 | SUBSTITUTED DIHYDROIMIDAZOLES AND THEIR USE IN THE TREATMENT OF TUMORS | NOVARTIS AG (CH) | 2008-06-05 | — | — | WO | claimed |
| CN-111801330-A | Fused ring compounds having dopamine D3 receptor antagonism | 盐野义制药株式会社 | 2020-10-20 | — | — | CN | disclosed |
| US-20100075966-A1 | Substituted Dihydroimidazoles and their Use in the Treatment of Tumors | NOVARTIS AG | 2010-03-25 | — | — | US | disclosed |
| EP-2097386-A2 | SUBSTITUTED DIHYDROIMIDAZOLES AND THEIR USE IN THE TREATMENT OF TUMORS | Novartis AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008065068-A2 | SUBSTITUTED DIHYDROIMIDAZOLES AND THEIR USE IN THE TREATMENT OF TUMORS | NOVARTIS AG (CH) | 2008-06-05 | — | — | WO | disclosed |