Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | WNT1 | P04628 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613929 | 0.92 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3608431 | 0.91 | NAMPT (0.56) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3606398 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL13504884 | 0.91 | NAMPT (0.60) | NAMPTRPS6KA2 | |
| SCHEMBL13504909 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL3596683 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3611305 | 0.91 | NAMPT (0.63) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL3612494 | 0.90 | NAMPT (0.59) | NAMPTRPS6KA2 | |
| Hydrochloric Acid SCHEMBL3610939 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3608032 | 0.89 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | claimed |
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | SMN1; SMN2 618/4885MEN1 3499/4885KMT2A 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.