Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 5/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601224 | 0.91 | SCD5 (0.51) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL3599020 | 0.90 | SMN1; SMN2 (0.57) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3599343 | 0.88 | ESR2 (0.46) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL3601198 | 0.88 | ESR2 (0.46) | MEN1KMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL3605404 | 0.88 | NAMPT (0.63) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3593773 | 0.87 | PTGER1 (0.54) | SMN1; SMN2ESR2NAMPTSCDSCD5 | |
| SCHEMBL3596504 | 0.87 | SMN1; SMN2 (0.57) | MEN1KMT2AMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL3606130 | 0.86 | KDM4E (0.50) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL3603596 | 0.85 | SCD (0.53) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3615745 | 0.85 | SCD (0.51) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | MEN1 3499/4885KMT2A 3500/4885KDM4E 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.