SCHEMBL3603406

SCHEMBL3603406

N#Cc1ccc(F)c2ccoc12

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.37
AR P10275 1/20 0.32
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 2/20 0.32
EGLN2 Q96KS0 1/20 0.31
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19631289 0.84 IMPDH2 (0.34) ARCYP19A1
SCHEMBL2122013 0.78 UPP1 (0.33) CYP19A1
SCHEMBL13453306 0.77 TSHR (0.38) CYP19A1
SCHEMBL24947172 0.73 IMPDH2 (0.31) CYP19A1
SCHEMBL29558914 0.73 CYP19A1 (0.36) CYP11B1CYP11B2CYP19A1
SCHEMBL24946531 0.73 CYP19A1 (0.36) CYP11B1CYP11B2CYP19A1
SCHEMBL29558995 0.73 CYP19A1 (0.36) CYP19A1
SCHEMBL2263808 0.73 ESR1 (0.35)
SCHEMBL2125034 0.73 IMPDH2 (0.54) AR
SCHEMBL24946530 0.73 CYP19A1 (0.36) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511329-A Aromatic group-containing polymer surfactant and preparation method and application thereof PETROCHINA CO LTD 2019-11-29 CN claimed
CN-110483299-A A kind of polymerisable surfactant of the structure containing aromatic hydrocarbons and preparation method thereof PETROCHINA CO LTD 2019-11-22 CN claimed
CN-106892914-B Organic electroluminescent compounds, organic electroluminescence device and its application 南京高光半导体材料有限公司 2019-02-01 CN claimed
US-5468897-A Bi-aromatic esters, a process for their preparation and their use in human or veterinary medicine and in cosmetic compositions CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) 1995-11-21 US claimed
US-5200550-A Administering for dermatologic, rheumatismal, respiratory or ophthalomologic disorders CENTRE INTERNATIONAL DE RECHERCES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) 1993-04-06 US claimed
WO-2024259241-A1 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF Transneural Therapeutics, Inc. (US) 2024-12-19 WO disclosed
EP-4384509-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO Pharmaceutical Co., Ltd. (JP) 2024-06-19 EP disclosed
EP-3398982-B1 PREPARATION METHOD FOR POLYMER AND APPLICATIONS THEREOF SOBUTE NEW MAT CO LTD (CN) 2023-08-23 EP disclosed
WO-2023017813-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2023-02-16 WO disclosed
US-10570253-B2 Preparation method for polymer and applications thereof SOBUTE NEW MATERIALS CO., LTD. (CN) 2020-02-25 US disclosed
CN-110511329-A Aromatic group-containing polymer surfactant and preparation method and application thereof PETROCHINA CO LTD 2019-11-29 CN disclosed
CN-110483299-A A kind of polymerisable surfactant of the structure containing aromatic hydrocarbons and preparation method thereof PETROCHINA CO LTD 2019-11-22 CN disclosed
US-5468897-A Bi-aromatic esters, a process for their preparation and their use in human or veterinary medicine and in cosmetic compositions CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) 1995-11-21 US disclosed
US-5332856-A Treatment of a dermatologic, rheumatismal, respiratory or ophthalmologic ailment CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) 1994-07-26 US disclosed
US-5212203-A Skin disorders CENTRE INTERNATIONAL DE RECHERCHES DERMATOGOLOGIQUES (C.I.R.D.) (FR) 1993-05-18 US disclosed
US-5200550-A Administering for dermatologic, rheumatismal, respiratory or ophthalomologic disorders CENTRE INTERNATIONAL DE RECHERCES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) 1993-04-06 US disclosed
US-4927928-A SKIN DISORDERS, EYES, ANTITUMOR CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1990-05-22 US disclosed
EP-0317983-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-31 EP disclosed
US-4067740-A Trithiocarbonates as sensitizers for silver halide emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-01-10 US disclosed
US-3931365-A AMMONIUM OR METAL THIOSULFATE, SULFITE OR BISULFITE STAUFFER CHEMICAL COMPANY (US) 1976-01-06 US disclosed