Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.56 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | PYGM | P11217 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 4/20 | 0.48 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603024 | 1.00 | ALOX15 (0.56) | ALOX15SMYD3PYGLPYGMF10 | |
| SCHEMBL3603019 | 1.00 | ALOX15 (0.56) | ALOX15SMYD3PYGLPYGMF10 | |
| SCHEMBL3605108 | 0.93 | ALOX15 (0.54) | ALOX15SMYD3PYGLPYGMF10 | |
| SCHEMBL3605105 | 0.93 | ALOX15 (0.54) | ALOX15SMYD3PYGLPYGMF10 | |
| Trifluoroacetic Acid SCHEMBL3610931 | 0.92 | SMYD3 (0.49) | ALOX15SMYD3PYGLPYGMF10 | |
| Trifluoroacetic Acid SCHEMBL3610457 | 0.92 | SMYD3 (0.49) | ALOX15SMYD3PYGLPYGMF10 | |
| SCHEMBL3603062 | 0.90 | SMYD3 (0.69) | SMYD3PYGLPYGMF10MLLT1 | |
| SCHEMBL3603066 | 0.90 | SMYD3 (0.69) | SMYD3PYGLPYGMF10MLLT1 | |
| SCHEMBL3609215 | 0.90 | SMYD3 (0.69) | SMYD3PYGLPYGMF10MLLT1 | |
| SCHEMBL3599029 | 0.85 | DRD4 (0.52) | SMYD3MLLT1HRH4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-02-11 | — | — | US | claimed |
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | IDO2, IDO1, INMT | ALOX15 1315/4885SMYD3 811/4885PYGL 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.