Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608439 | 0.90 | HDAC6 (0.60) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3611422 | 0.90 | HDAC6 (0.62) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3601082 | 0.83 | HDAC6 (0.66) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3605153 | 0.82 | ALDH1A1 (0.63) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3613096 | 0.82 | HDAC6 (0.61) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3598797 | 0.82 | HDAC1 (0.56) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3612223 | 0.82 | HDAC6 (0.83) | HDAC6HDAC1POLBTDP1HDAC8 | |
| SCHEMBL3596570 | 0.79 | HDAC1 (0.57) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3612530 | 0.78 | HDAC6 (0.62) | HDAC6HDAC1ALDH1A1POLBTDP1 | |
| SCHEMBL3603443 | 0.77 | HDAC1 (0.60) | HDAC6HDAC1ALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152188-A1 | Novel Heterocyclic Compounds | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-06-17 | — | — | US | claimed |
| US-20100152188-A1 | Novel Heterocyclic Compounds | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152188-A1 | Novel Heterocyclic Compounds | CYP11B2, CYP3A5, CYP11B1 | HDAC6 90/4885HDAC1 307/4885ALDH1A1 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.