Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605612 | 0.89 | CNR1 (0.43) | CNR1SLC6A2SLC6A4SLC6A3DPP4 | |
| SCHEMBL3594733 | 0.88 | CXCR2 (0.44) | CNR1MDM4TP53MDM2HSD11B1 | |
| SCHEMBL3595829 | 0.85 | CYP3A4 (0.44) | MDM4TP53MDM2DPP4DPP8 | |
| SCHEMBL3595338 | 0.84 | PNMT (0.41) | CNR1TAAR1DPP4DPP8 | |
| SCHEMBL3605880 | 0.84 | MDM4 (0.43) | SLC6A2SLC6A4SLC6A3MDM4TP53 | |
| SCHEMBL3597273 | 0.83 | CXCR2 (0.40) | CNR1MDM4TP53MDM2HSD11B1 | |
| SCHEMBL3599359 | 0.83 | CXCR2 (0.40) | CNR1MDM4TP53MDM2HSD11B1 | |
| SCHEMBL3600935 | 0.82 | TP53 (0.45) | MDM4TP53MDM2HSD11B1DPP4 | |
| SCHEMBL3600919 | 0.82 | MDM4 (0.42) | CNR1KDM4CMDM4TP53MDM2 | |
| SCHEMBL3602324 | 0.82 | CYP11B1 (0.41) | CNR1TP53HSD11B1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |