Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | PPOX | P50336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604694 | 1.00 | ALDH1A1 (0.33) | ALDH1A1NPC1RAB9AFAAHGPBAR1 | |
| SCHEMBL3612153 | 0.89 | POLB (0.34) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3612147 | 0.89 | POLB (0.34) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3596680 | 0.88 | SMN1; SMN2 (0.34) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3596688 | 0.88 | SMN1; SMN2 (0.34) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3610167 | 0.83 | KDM4E (0.36) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3610174 | 0.83 | KDM4E (0.36) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3607755 | 0.81 | L3MBTL1 (0.37) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3607759 | 0.81 | L3MBTL1 (0.37) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD | |
| SCHEMBL3605951 | 0.79 | KDM4E (0.35) | ALDH1A1GPBAR1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016396-A1 | PYRAZOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128138-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016396-A1 | PYRAZOLE COMPOUND | SLC5A1, SLC5A2, GLP1R | ALDH1A1 365/4885NPC1 985/4885RAB9A 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.