Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.64 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | PI4KA | P42356 | 3/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788793 | 0.78 | PIK3CD (1.00) | PIK3CDPIK3R1ADORA2APIK3CBPIK3CG | |
| SCHEMBL360489 | 0.77 | PIK3CD (1.00) | PIK3CDPIK3R1ADORA2API4KAPI4K2B | |
| SCHEMBL2438140 | 0.76 | PIK3CD (0.66) | PIK3CDPIK3R1ADORA2APIK3CBPIK3CG | |
| SCHEMBL4229672 | 0.75 | ALDH1A1 (0.57) | PIK3CDALDH1A1SMN1; SMN2MEN1GAA | |
| SCHEMBL1755808 | 0.73 | PIK3CD (0.70) | PIK3CDPIK3R1ADORA2APIK3CBPIK3CG | |
| SCHEMBL4234298 | 0.73 | ALDH1A1 (0.55) | PIK3CDALDH1A1SMN1; SMN2MEN1GAA | |
| SCHEMBL4232766 | 0.73 | ALDH1A1 (0.55) | PIK3CDALDH1A1SMN1; SMN2MEN1GAA | |
| SCHEMBL27789328 | 0.73 | ALDH1A1 (0.57) | PIK3CDALDH1A1SMN1; SMN2MEN1GAA | |
| SCHEMBL4233567 | 0.73 | ALDH1A1 (0.57) | PIK3CDALDH1A1SMN1; SMN2MEN1GAA | |
| SCHEMBL5607746 | 0.71 | PIK3CD (0.67) | PIK3CDPIK3R1ADORA2APIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009452-A1 | THE ROLE OF P13K P110 DELTA SIGNALING IN RETROVIRAL INFECTION AND REPLICATION | PHILADELPHIA HEALTH & EDUCATION CORPORATION (US) | 2012-01-19 | — | — | WO | disclosed |