Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 4/20 | 0.40 |
| ▸ | CLK1 | P49759 | 4/20 | 0.40 |
| ▸ | CLK2 | P49760 | 4/20 | 0.40 |
| ▸ | CLK3 | P49761 | 4/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18713740 | 0.83 | TAS1R3 (0.45) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL19333368 | 0.82 | NTRK1 (0.53) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL4713744 | 0.81 | NPC1 (0.49) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL12600125 | 0.79 | RAB9A (0.47) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL20511819 | 0.78 | NTRK1 (0.42) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL277372 | 0.78 | NPC1 (0.50) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL21025002 | 0.76 | TAS1R3 (0.51) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL21164379 | 0.75 | FFAR1 (0.54) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL24347730 | 0.75 | NPC1 (0.45) | TAS1R3TAS1R1NPC1RAB9AKDM4E | |
| SCHEMBL21123817 | 0.75 | NPC1 (0.45) | TAS1R3TAS1R1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |