Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.37 |
| ▸ | TFEB | P19484 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606823 | 0.85 | NFE2L2 (0.47) | NFE2L2BACE1IAPPTFEBMAPT | |
| SCHEMBL3606819 | 0.85 | NFE2L2 (0.47) | NFE2L2BACE1IAPPTFEBMAPT | |
| SCHEMBL3605647 | 0.81 | NFE2L2 (0.51) | NFE2L2BACE1IAPPTFEBMAPT | |
| SCHEMBL3605646 | 0.81 | NFE2L2 (0.51) | NFE2L2BACE1IAPPTFEBMAPT | |
| SCHEMBL3129248 | 0.78 | HTT (0.55) | NFE2L2BACE1TFEBMAPTNPC1 | |
| SCHEMBL3129242 | 0.78 | HTT (0.55) | NFE2L2BACE1TFEBMAPTNPC1 | |
| SCHEMBL3126050 | 0.75 | NFE2L2 (0.45) | NFE2L2BACE1TFEBMAPTNPC1 | |
| SCHEMBL3126052 | 0.75 | NFE2L2 (0.45) | NFE2L2BACE1TFEBMAPTNPC1 | |
| SCHEMBL3129600 | 0.74 | NFE2L2 (0.44) | NFE2L2BACE1TFEBMAPTNPC1 | |
| SCHEMBL3129598 | 0.74 | NFE2L2 (0.44) | NFE2L2BACE1TFEBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674825-B2 | Dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2010-03-09 | — | — | US | disclosed |