Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596977 | 0.88 | USP30 (0.58) | GPR119USP30 | |
| SCHEMBL22390396 | 0.87 | USP30 (0.52) | GPR119USP30 | |
| SCHEMBL22390394 | 0.87 | USP30 (0.52) | GPR119USP30 | |
| SCHEMBL3609803 | 0.86 | USP30 (0.52) | USP30 | |
| SCHEMBL31524262 | 0.86 | USP30 (0.52) | GPR119USP30 | |
| SCHEMBL23897991 | 0.86 | USP30 (0.52) | GPR119USP30 | |
| SCHEMBL20616391 | 0.86 | USP30 (0.52) | GPR119USP30 | |
| SCHEMBL3604813 | 0.85 | USP30 (0.59) | GPR119USP30 | |
| SCHEMBL22390313 | 0.85 | GPR119 (0.53) | GPR119USP30 | |
| SCHEMBL22390314 | 0.85 | GPR119 (0.53) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004249-A1 | Bicyclic heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2039695-A1 | BICYCLIC HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004249-A1 | Bicyclic heterocyclic compound and use thereof | HTR2C, HTR5A, HTR2A | GPR119 268/4885USP30 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.