Glycerin

Glycerin

SCHEMBL3607211

O=C(O)CCCCCCCCCCC(=O)O.OCC(O)CO

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.63
LMNA P02545 3/20 0.63
NFKB1 P19838 1/20 0.63
PMP22 Q01453 1/20 0.63
GPR84 Q9NQS5 7/20 0.59
FFAR1 O14842 3/20 0.59
FFAR4 Q5NUL3 3/20 0.59
PPARG P37231 6/20 0.50
PPARD Q03181 6/20 0.50
PPARA Q07869 6/20 0.50
HDAC11 Q96DB2 5/20 0.50
ALDH1A1 P00352 3/20 0.50
SLC22A6 Q4U2R8 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
FABP4 P15090 2/20 0.50
ALOX15 P16050 2/20 0.50
PTPN1 P18031 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL27596618 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL270082 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL30008072 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL31615119 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL1495263 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Pimelic Acid SCHEMBL29894654 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Glycerin SCHEMBL29687651 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL31652315 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Glycerin SCHEMBL28489790 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Octanedioate SCHEMBL1906246 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115094528-A Mechanical active fiber for promoting differentiation of stem cell into tendon and preparation method thereof 东华大学 2022-09-23 CN claimed
CN-114668561-A Intelligent minimally invasive nucleus pulposus implantation stent capable of inducing regeneration and preparation and driving methods 北京航空航天大学 2022-06-28 CN claimed
US-20100196322-A1 POLYMER FOR TISSUE ENGINEERING APPLICATIONS AND DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2010-08-05 US claimed
CN-114668561-A Intelligent minimally invasive nucleus pulposus implantation stent capable of inducing regeneration and preparation and driving methods 北京航空航天大学 2022-06-28 CN disclosed
US-8236350-B2 Polymer for tissue engineering applications and drug delivery THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2012-08-07 US disclosed
US-20100196322-A1 POLYMER FOR TISSUE ENGINEERING APPLICATIONS AND DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2010-08-05 US disclosed
US-6017566-A POLYESTER THAT IS PRODUCED THROUGH REACTION OF GLYCEROL AND AT LEAST ONE ACID CHOSEN FROM CITRIC ACID, FUMARIC ACID, ADIPIC ACID, MALIC ACID, SUCCINIC ACID, SUBERIC ACID, SEBACIC ACID, DODECANEDIOIC ACID, GLUCARIC ACID, AZELAIC ACID, TARTARIC ACID WM. WRIGLEY JR. COMPANY (US) 2000-01-25 US disclosed
WO-1998017124-A1 GUM BASE AND CHEWING GUM CONTAINING EDIBLE POLYESTERS WM. WRIGLEY JR. COMPANY (US) 1998-04-30 WO disclosed