Azelaic Acid

Azelaic Acid

SCHEMBL1495263

O=C(O)CCCCCCCC(=O)O.OCC(O)CO

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.63
LMNA P02545 3/20 0.63
NFKB1 P19838 1/20 0.63
PMP22 Q01453 1/20 0.63
GPR84 Q9NQS5 7/20 0.59
FFAR1 O14842 3/20 0.59
FFAR4 Q5NUL3 3/20 0.59
PPARG P37231 6/20 0.50
PPARD Q03181 6/20 0.50
PPARA Q07869 6/20 0.50
HDAC11 Q96DB2 5/20 0.50
ALDH1A1 P00352 3/20 0.50
SLC22A6 Q4U2R8 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
FABP4 P15090 2/20 0.50
ALOX15 P16050 2/20 0.50
PTPN1 P18031 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL27596618 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL270082 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL30008072 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Glycerin SCHEMBL3607211 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL31615119 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Pimelic Acid SCHEMBL29894654 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Glycerin SCHEMBL29687651 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL31652315 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Glycerin SCHEMBL28489790 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Octanedioate SCHEMBL1906246 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192944-A1 METHOD OF PREPARING A DEGRADABLE PRODUCT UNIV NAT TSING HUA (TW) 2023-06-22 US claimed
CN-113278273-A Degradable microparticle, degradable product containing same and application 王洁 2021-08-20 CN claimed
US-9351918-B2 Polyglycerol-azelaic acid polyesters for cosmetic applications GIULIANI S.P.A. (IT) 2016-05-31 US claimed
EP-2880075-B1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS GIULIANI SPA (IT) 2016-05-25 EP claimed
US-20150196480-A1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS GUILIANI S.P.A. (IT) 2015-07-16 US claimed
EP-2880075-A1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS Giuliani S.p.A. (IT) 2015-06-10 EP claimed
WO-2014020158-A1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS GIULIANI S.P.A. (IT) 2014-02-06 WO claimed
US-20230192944-A1 METHOD OF PREPARING A DEGRADABLE PRODUCT UNIV NAT TSING HUA (TW) 2023-06-22 US disclosed
US-20230192944-A1 METHOD OF PREPARING A DEGRADABLE PRODUCT UNIV NAT TSING HUA (TW) 2023-06-22 US disclosed
CN-116059133-A Transparent shaping eyebrow glue and preparation method thereof 上海绵花棠生物科技有限公司 2023-05-05 CN disclosed
CN-113278273-A Degradable microparticle, degradable product containing same and application 王洁 2021-08-20 CN disclosed
US-9351918-B2 Polyglycerol-azelaic acid polyesters for cosmetic applications GIULIANI S.P.A. (IT) 2016-05-31 US disclosed
US-9351918-B2 Polyglycerol-azelaic acid polyesters for cosmetic applications GIULIANI S.P.A. (IT) 2016-05-31 US disclosed
EP-2880075-A1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS Giuliani S.p.A. (IT) 2015-06-10 EP disclosed
WO-2014020158-A1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS GIULIANI S.P.A. (IT) 2014-02-06 WO disclosed
WO-2014020158-A1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS GIULIANI S.P.A. (IT) 2014-02-06 WO disclosed
EP-2470220-A1 POLYMER ADHESIVE FILM FOR DIRECTED CELLULAR GROWTH Innovative Health Technologies, Llc (US) 2012-07-04 EP disclosed
WO-2011025866-A1 POLYMER ADHESIVE FILM FOR DIRECTED CELLULAR GROWTH INNOVATIVE HEALTH TECHNOLOGIES, LLC (US) 2011-03-03 WO disclosed
US-4542052-A IMAGE AND ADHESIVE LAYER RELEASABLE ADHERED TO SUBSTRATE OVERCOATED WITH NON-ADHESIVE LAYER RECEPTIVE TO TONER ESSELTE PENDAFLEX CORPORATION (US) 1985-09-17 US disclosed
US-4070523-A POLYKETONE RESINS, RELEASE COATING BORDEN, INC. (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150196480-A1 POLYGLYCEROL-AZELAIC ACID POLYESTERS FOR COSMETIC APPLICATIONS DAGLA, GLA, MGLL TSHR 1959/4885LMNA 2919/4885NFKB1 3765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.