Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL27596618 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL270082 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Glycerin SCHEMBL3607211 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL31615119 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL1495263 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Pimelic Acid SCHEMBL29894654 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Glycerin SCHEMBL29687651 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL31652315 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Glycerin SCHEMBL28489790 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Octanedioate SCHEMBL1906246 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024256602-A1 | METHOD FOR STIMULATING LATEX PRODUCTION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-12-19 | — | — | WO | claimed |
| WO-2024256602-A1 | METHOD FOR STIMULATING LATEX PRODUCTION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-12-19 | — | — | WO | disclosed |
| US-11458230-B2 | Method comprising contacting tissue with a cross-linkable polyester prepolymer | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11458230-B2 | Method comprising contacting tissue with a cross-linkable polyester prepolymer | COL14A1, ILK, COL1A1 | SLC6A2 4160/4885SLC6A3 3946/4885TSHR 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.