Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL6799208 | 0.89 | ALDH1A1 (0.45) | ALDH1A1LMNAHSD17B10POLBTSHR | |
| SCHEMBL30049090 | 0.82 | POLB (0.40) | ALDH1A1LMNAHSD17B10POLBTSHR | |
| Hexane SCHEMBL19611385 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10POLB | |
| SCHEMBL21554071 | 0.76 | POLB (0.36) | ALDH1A1LMNAHSD17B10POLBCYP2C19 | |
| SCHEMBL28139614 | 0.76 | MGAM (0.39) | ALDH1A1LMNAHSD17B10POLBTSHR | |
| Ethyl Acetate SCHEMBL7990825 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL28154238 | 0.73 | LMNA (0.42) | ALDH1A1LMNAHSD17B10POLBTSHR | |
| SCHEMBL22844448 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10POLBTSHR | |
| SCHEMBL27513818 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10POLBTSHR | |
| SCHEMBL234751 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016396-A1 | PYRAZOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128138-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | ALDH1A1 783/4885LMNA 2989/4885HSD17B10 151/4885 |
| US-20100016396-A1 | PYRAZOLE COMPOUND | SLC5A1, SLC5A2, GLP1R | ALDH1A1 365/4885LMNA 4306/4885HSD17B10 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.