Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6053093 | 0.98 | KMT2A (0.47) | KMT2AKDM4EMETAP2PLAUNCF1 | |
| SCHEMBL5133573 | 0.91 | KDM4E (0.45) | KMT2AKDM4EMETAP2PLAUNCF1 | |
| SCHEMBL3212638 | 0.87 | METAP2 (0.57) | KMT2AKDM4EMETAP2PLAUNCF1 | |
| SCHEMBL10437736 | 0.85 | METAP2 (0.45) | KMT2AKDM4EMETAP2PLAUNCF1 | |
| SCHEMBL11050450 | 0.85 | PDE10A (0.43) | KMT2AKDM4EMETAP2PLAUNCF1 | |
| SCHEMBL7133311 | 0.85 | KCNH2 (0.56) | KMT2AKDM4EMETAP2PLAUNCF1 | |
| SCHEMBL10529725 | 0.83 | ALDH1A1 (0.48) | KMT2AALDH1A1TDP1PIM1POLB | |
| SCHEMBL11057999 | 0.83 | BCHE (0.43) | KMT2AKDM4EMETAP2PDE10APDE4D | |
| SCHEMBL6269837 | 0.82 | CYSLTR1 (0.49) | KMT2AKDM4EALDH1A1CYP3A4PDE10A | |
| SCHEMBL8516691 | 0.82 | PDE10A (0.52) | KMT2AKDM4EMETAP2ALDH1A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143055-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | Bridgestone Corporation (JP) | 2017-03-22 | — | — | EP | claimed |
| WO-2015175280-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | WO | claimed |
| US-6831061-B2 | Anticancer agents; histone deactylase inhibitor | Lee, Hyang Woo (KR) | 2004-12-14 | — | — | US | claimed |
| US-20040014647-A1 | Apicidin-derivatives, their synthetic methods and anti-tumor compositions containing them | LEE, SEOK YONG (KR) | 2004-01-22 | — | — | US | claimed |
| WO-2002051846-A1 | APICIDIN-DERIVATIVES, THEIR SYNTHETIC METHODS, AND ANTITUMOR COMPOSITIONS CONTAINING THE SAME | ZEE, OK PYO (KR) | 2002-07-04 | — | — | WO | claimed |
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | claimed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | claimed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | claimed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | claimed |
| EP-0377532-B1 | THIOFORMAMIDE DERIVATIVES | MAY AND BAKER LIMITED (GB) | 1992-07-29 | — | — | EP | claimed |
| US-5104883-A | Cardiovascular, respiratory, gastrointestirol, urogenital disorders; baldness; premature labor | MAY & BAKER LIMITED (GB) | 1992-04-14 | — | — | US | claimed |
| EP-0377532-A1 | Thioformamide derivatives | MAY AND BAKER LIMITED (GB) | 1990-07-11 | — | — | EP | claimed |
| EP-0292352-A2 | Macrolide derivatives, process for their preparation and their pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 1988-11-23 | — | — | EP | claimed |
| US-4425404-A | MULTILAYER, PROTECTIVE COATINGS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1984-01-10 | — | — | US | claimed |
| JP-63060952-A | — | — | None | — | — | JP | disclosed |
| JP-56052722-A | — | — | None | — | — | JP | disclosed |
| US-20240148918-A1 | Loading of Alginate Microspheres | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-05-09 | — | — | US | disclosed |
| EP-0028346-B1 | TRISUBSTITUTED BENZYL-OXIME ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1982-08-04 | — | — | EP | disclosed |
| EP-0028346-A1 | Trisubstituted benzyl-oxime ethers, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| JP-S5652722-A | LIQUID CRYSTAL DISPLAY PANEL AND ITS PRODUCTION | RICOH ELEMEX CORP | 1981-05-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014647-A1 | Apicidin-derivatives, their synthetic methods and anti-tumor compositions containing them | HDAC1, AADAC, HDAC3 | KMT2A 404/4885KDM4E 331/4885METAP2 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.