Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629010 | 0.86 | PTGS2 (0.58) | PTGS2PTPRCGABRA1GABRB2NPC1 | |
| SCHEMBL2692579 | 0.86 | CA12 (0.59) | PTGS2PTPRCGABRA1GABRB2NPC1 | |
| SCHEMBL6291802 | 0.82 | CA12 (0.56) | PTGS2PTPRCGABRA1GABRB2NPC1 | |
| SCHEMBL404584 | 0.80 | PTGS2 (0.66) | PTGS2PTPRCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30009937 | 0.80 | PTGS2 (0.66) | PTGS2PTPRCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL962955 | 0.78 | PTPRC (0.54) | PTGS2PTPRCGABRA1GABRB2NPC1 | |
| SCHEMBL30469371 | 0.78 | CYP19A1 (0.58) | PTGS2PTPRCGABRA1GABRB2NPC1 | |
| SCHEMBL13376227 | 0.78 | GAA (0.67) | PTGS2PTPRCGABRA1GABRB2NPC1 | |
| SCHEMBL980270 | 0.78 | CYP19A1 (0.58) | PTGS2PTPRCGABRA1GABRB2NPC1 | |
| SCHEMBL22162812 | 0.78 | CA12 (0.58) | PTGS2PTPRCNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105714-A1 | Furanone Compounds and Methods of Making and Using The Same | BIOGEN IDEC MA INC. (US) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105714-A1 | Furanone Compounds and Methods of Making and Using The Same | ALK, ACVR1, ACVR1B | PTGS2 962/4885PTPRC 3111/4885GABRA1 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.