Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 3/20 | 0.38 |
| ▸ | CA6 | P23280 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616823 | 0.99 | HTT (0.39) | HTTMAPK1TDP1MAPTTP53 | |
| SCHEMBL3612057 | 0.95 | KDM4E (0.39) | MAPK1MAPTTP53LMNACASP1 | |
| SCHEMBL3602148 | 0.83 | HTT (0.46) | HTTMAPK1TDP1MAPTTP53 | |
| SCHEMBL3609243 | 0.82 | HTT (0.44) | HTTMAPK1TDP1MAPTTP53 | |
| SCHEMBL3615257 | 0.81 | KMT2A (0.48) | HTTMAPK1TDP1MAPTTP53 | |
| SCHEMBL3616584 | 0.80 | TDP1 (0.42) | HTTMAPK1TDP1MAPTTP53 | |
| SCHEMBL3609888 | 0.80 | HSD17B10 (0.48) | TDP1MAPTTP53LMNACASP1 | |
| SCHEMBL3605244 | 0.79 | ALDH1A1 (0.49) | HTTTDP1MAPTTP53LMNA | |
| SCHEMBL3607440 | 0.79 | HSD17B10 (0.47) | TDP1MAPTTP53LMNACASP1 | |
| SCHEMBL2348809 | 0.78 | BRAF (0.46) | HTTMAPK1TDP1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222322-A1 | Non-Nucleoside Reverse Transcriptase Inhibitors | MERCK & CO., INC. (US) | 2010-09-02 | — | — | US | claimed |
| EP-1899340-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | Merck & Co., Inc. (US) | 2008-03-19 | — | — | EP | claimed |
| WO-2007002368-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | claimed |
| CN-101884898-B | Substrate for biochip and method for manufacturing substrate for biochip | YAMATAKE CORP | 2013-05-01 | — | — | CN | disclosed |
| CN-101884899-B | Substrate for biochip and manufacturing method of the same | YAMATAKE CORP | 2013-04-03 | — | — | CN | disclosed |
| US-8287939-B2 | Method for manufacturing substrate for biochip | AZBIL CORPORATION (JP) | 2012-10-16 | — | — | US | disclosed |
| CN-101001692-B | Biochip substrate and method of manufacturing biochip substrate | YAMATAKE CO LTD | 2011-05-11 | — | — | CN | disclosed |
| US-20100288727-A1 | METHOD FOR MANUFACTURING SUBSTRATE FOR BIOCHIP | YAMATAKE CORPORATION (JP) | 2010-11-18 | — | — | US | disclosed |
| CN-101884899-A | The method of biochip substrate and the substrate of manufacturing biochip | YAMATAKE CORP | 2010-11-17 | — | — | CN | disclosed |
| CN-101884898-A | The method of biochip substrate and the substrate of manufacturing biochip | YAMATAKE CORP | 2010-11-17 | — | — | CN | disclosed |
| US-7807105-B2 | Substrate for biochip | YAMATAKE CORPORATION (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20100222322-A1 | Non-Nucleoside Reverse Transcriptase Inhibitors | MERCK & CO., INC. (US) | 2010-09-02 | — | — | US | disclosed |
| US-20080253928-A1 | Substrate surface capable of reacting with biological substances and having a region not reacting with the biological substances;sunken bottomed wells formed in the surface; and a layer capable of reacting with the biological substances having a surface exposed only at the bottoms of the bottomed wells | YAMATAKE CORPORATION (JP) | 2008-10-16 | — | — | US | disclosed |
| CN-101001692-A | Biochip substrate and method of manufacturing biochip substrate | YAMATAKE CORP (JP) | 2007-07-18 | — | — | CN | disclosed |
| WO-2006006262-A1 | SUBSTRATE FOR BIOCHIP AND METHOD FOR MANUFACTURING SUBSTRATE FOR BIOCHIP | YAMATAKE CORPORATION (JP) | 2006-01-19 | — | — | WO | disclosed |
| EP-1614460-A1 | Substrate for biochips | Yamatake Corporation (JP) | 2006-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222322-A1 | Non-Nucleoside Reverse Transcriptase Inhibitors | IDO1, IDO2, INMT | HTT 2637/4885MAPK1 3023/4885TDP1 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.