⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380065 | 0.88 | KCNH3 (0.33) | — | |
| SCHEMBL4502053 | 0.86 | CYP1A2 (0.36) | — | |
| SCHEMBL15821790 | 0.86 | FKBP1A (0.34) | — | |
| SCHEMBL10932131 | 0.84 | CYP1A2 (0.35) | — | |
| SCHEMBL11367183 | 0.84 | CYP1A2 (0.35) | — | |
| SCHEMBL11364233 | 0.84 | CYP1A2 (0.35) | — | |
| SCHEMBL11380990 | 0.84 | CYP1A2 (0.35) | — | |
| SCHEMBL2514383 | 0.82 | — | — | |
| SCHEMBL8651422 | 0.82 | — | — | |
| SCHEMBL2034414 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423479-A1 | SURFACE MODIFIED CARBON BLACK | Lexmark International, Inc. (US) | 2004-06-02 | — | — | EP | claimed |
| WO-2003011982-A1 | SURFACE MODIFIED CARBON BLACK | LEXMARK INTERNATIONAL, INC. (US) | 2003-02-13 | — | — | WO | claimed |
| US-6488818-B1 | DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | claimed |
| EP-0994112-B1 | Method for separating contaminants from 3-(2'-acetoxy-ethyl)-dihydro-2(3h)furanone | BASF AG (DE) | 2002-07-24 | — | — | EP | claimed |
| EP-1037884-B1 | METHOD FOR SEPARATING CONTAMINANTS FROM 3-(2'-ACETOXY-ETHYL-DIHYDRO-2(3H)FURANONE | BASF AG (DE) | 2002-03-13 | — | — | EP | claimed |
| US-6201135-B1 | PREPARING 3-(2'-ACETOXYETHYL)DIHYDRO-2(3H)-FURANONE CONTAINING UNDESIRABLE IMPURITIES IN A MANNER KNOWN PER SE BY ACETYLATING 3-(2'-HYDROXYETHYL)-DIHYDRO-2-(3H)-FURANONE, TREATING IT WITH STRONG MINERAL ACIDS, REMOVING DECOMPOSITION PRODUCTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | claimed |
| EP-0994112-A1 | Method for separating contaminants from 3-(2'-acetoxy-ethyl)-dihydro-2(3h)furanone | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-19 | — | — | EP | claimed |
| EP-0584663-B1 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF AG (DE) | 1998-02-25 | — | — | EP | claimed |
| EP-0584631-B1 | Process of preparing 3-(2'-acyloxyethyl)-dihydro-2(3H)furanones | BASF AG (DE) | 1997-07-16 | — | — | EP | claimed |
| EP-0588224-B1 | Process for the preparation of 3-(2'-oxyethyl)-dihydro-2-(3H)furanones | BASF AG (DE) | 1996-12-18 | — | — | EP | claimed |
| US-5466831-A | Preparation of 3-(2-acyloxyethyl)-dihydro-2(3H)furanones | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-14 | — | — | US | claimed |
| US-5371246-A | Preparation of tetrahydropyran-4-carboxylic acid and esters thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | claimed |
| US-5350863-A | Preparation of 3-(2'-oxyethyl)dihydro-2(3H)furanones | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-27 | — | — | US | claimed |
| EP-0588224-A1 | Process for the preparation of 3-(2'-oxyethyl)-dihydro-2-(3H)furanones | BASF Aktiengesellschaft (DE) | 1994-03-23 | — | — | EP | claimed |
| EP-0584663-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | claimed |
| EP-0584631-A1 | Process of preparing 3-(2'-acyloxyethyl)-dihydro-2(3H)furanones | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | claimed |
| US-20200179428-A1 | CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2020-06-11 | — | — | US | disclosed |
| US-20100105929-A1 | PROCESS FOR THE PREPARATION OF y-BUTYROLACTONES | LONZA LTD. (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-0284969-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid esters | BASF Aktiengesellschaft (DE) | 1988-10-05 | — | — | EP | disclosed |
| EP-0246581-A2 | Process for the preparation of alpha-substituted gamma-butyrolactones | BASF Aktiengesellschaft (DE) | 1987-11-25 | — | — | EP | disclosed |