Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 13/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 4/20 | 0.31 |
| ▸ | MMP14 | P50281 | 3/20 | 0.31 |
| ▸ | MMP13 | P45452 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103292 | 1.00 | CCR1 (0.33) | CCR1ADAMTS5CFDMMP2MMP14 | |
| SCHEMBL3608778 | 1.00 | CCR1 (0.33) | CCR1ADAMTS5CFDMMP2MMP14 | |
| SCHEMBL3608772 | 1.00 | CCR1 (0.33) | CCR1ADAMTS5CFDMMP2MMP14 | |
| SCHEMBL106649 | 0.88 | PDK1 (0.38) | ADAMTS5CFD | |
| SCHEMBL105247 | 0.88 | PDK1 (0.38) | ADAMTS5CFD | |
| SCHEMBL106650 | 0.88 | PDK1 (0.38) | ADAMTS5CFD | |
| SCHEMBL105421 | 0.87 | — | — | |
| SCHEMBL3594669 | 0.87 | — | — | |
| SCHEMBL3594672 | 0.87 | — | — | |
| SCHEMBL3594674 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551985-B2 | Carbinol derivatives having heterocyclic linker | KOWA COMPANY, LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| US-20100280013-A1 | CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER | KOWA COMPANY, LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280013-A1 | CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER | NR1H2, NR1H3, CCR2 | CCR1 10/4885ADAMTS5 4612/4885CFD 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.