Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 17/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607633 | 0.89 | XIAP (0.53) | XIAPMEN1KMT2ATDP1 | |
| SCHEMBL3596631 | 0.81 | SOAT1 (0.44) | XIAP | |
| SCHEMBL3601025 | 0.79 | XIAP (0.39) | XIAPMEN1KMT2ATDP1 | |
| SCHEMBL3609812 | 0.76 | XIAP (0.55) | XIAP | |
| SCHEMBL3608616 | 0.76 | RORC (0.39) | XIAP | |
| SCHEMBL3611817 | 0.76 | GHSR (0.44) | XIAP | |
| SCHEMBL3612495 | 0.75 | XIAP (0.50) | XIAPMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3613026 | 0.75 | RORC (0.38) | XIAP | |
| SCHEMBL3612823 | 0.74 | XIAP (0.44) | XIAP | |
| SCHEMBL3612848 | 0.74 | XIAP (0.47) | XIAPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222348-A1 | QUINOLINONE DERIVATIVES AS PARP INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222348-A1 | QUINOLINONE DERIVATIVES AS PARP INHIBITORS | PARP1, PARP2, PARP11 | XIAP 333/4885ESR1 554/4885ESR2 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.