Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.39 |
| ▸ | EIF4E | P06730 | 2/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13408085 | 0.92 | CDC7 (0.41) | EIF4EMKNK1MKNK2CDC7PIM1 | |
| Trifluoroacetic Acid SCHEMBL3621523 | 0.83 | MAPKAPK2 (0.47) | BACE1IRAK4MKNK1MKNK2CDC7 | |
| SCHEMBL13442759 | 0.83 | MAPKAPK2 (0.38) | EIF4EMKNK1MKNK2KDM5AKDM4C | |
| SCHEMBL3615206 | 0.81 | GPR119 (0.42) | BACE1 | |
| Trifluoroacetic Acid SCHEMBL3616676 | 0.81 | MAPKAPK2 (0.39) | IRAK4CDC7PIM1CDK9PRKD1 | |
| Trifluoroacetic Acid SCHEMBL3618304 | 0.80 | PRKD1 (0.39) | IRAK4CDC7PIM1CDK9PRKD1 | |
| Trifluoroacetic Acid SCHEMBL3610007 | 0.80 | PIM1 (0.37) | IRAK4CDC7PIM1CDK9MAPKAPK2 | |
| Trifluoroacetic Acid SCHEMBL3615875 | 0.79 | ATR (0.35) | IRAK4CDC7PIM1CDK9PRKD1 | |
| Trifluoroacetic Acid SCHEMBL3619396 | 0.79 | IRAK4 (0.38) | IRAK4CDC7PIM1CDK9PRKD1 | |
| SCHEMBL3609154 | 0.79 | MKNK1 (0.38) | BACE1IRAK4EIF4EMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105664-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | claimed |
| US-20100105664-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105664-A1 | ORGANIC COMPOUNDS | SLCO1B3, SLCO1B1, SLC10A6 | BACE1 680/4885IRAK4 3656/4885EIF4E 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.