Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483690 | 0.86 | MAPT (0.61) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16095299 | 0.84 | KDM4E (0.57) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3611196 | 0.81 | KDM4E (0.67) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3602085 | 0.78 | MAPK14 (0.65) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3601307 | 0.78 | PTPN1 (0.58) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6312102 | 0.78 | MAPT (0.67) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27535968 | 0.77 | KDM4E (0.66) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16095667 | 0.76 | MAPT (0.49) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL656187 | 0.76 | MAPT (0.80) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12483440 | 0.75 | GSK3B (0.53) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
| WO-2006092059-A1 | DESIGN AND SYNTHESIS OF NOVEL ANTIMICROBIALS | WU FAN (CA) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | MAPT 4883/4885KDM4E 4236/4885RAB9A 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.