Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | IKBKB | O14920 | 7/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313705 | 0.80 | IKBKB (0.77) | PTPN1IKBKBCHUKCYP1A2CYP3A4 | |
| SCHEMBL3609405 | 0.78 | MAPT (0.72) | IKBKBCHUKCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17226334 | 0.78 | PTPN1 (0.56) | PTPN1IKBKBCHUKCYP1A2CYP3A4 | |
| SCHEMBL6348871 | 0.78 | PTPN1 (0.56) | PTPN1IKBKBCHUKCYP1A2CYP3A4 | |
| SCHEMBL3597485 | 0.77 | SNCA (0.53) | PTPN1IKBKBCHUKCYP1A2CYP3A4 | |
| SCHEMBL14156991 | 0.75 | DAO (0.48) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3594365 | 0.74 | IKBKB (0.42) | PTPN1IKBKBCHUKCYP1A2CYP3A4 | |
| SCHEMBL13715918 | 0.74 | PTPN1 (0.67) | PTPN1IKBKBCHUKCYP1A2CYP3A4 | |
| SCHEMBL6311384 | 0.74 | PTPN1 (1.00) | PTPN1IKBKBKDM4EMAPTMEN1 | |
| SCHEMBL6264668 | 0.74 | PTPN1 (0.52) | PTPN1IKBKBCHUKCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | PTPN1 2322/4885IKBKB 1465/4885CHUK 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.