⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29597944 | 0.84 | — | — | |
| SCHEMBL3601323 | 0.83 | — | — | |
| SCHEMBL29598472 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL30888304 | 0.79 | — | — | |
| SCHEMBL1188811 | 0.79 | — | — | |
| SCHEMBL30951446 | 0.77 | PDXK (0.33) | — | |
| SCHEMBL22939969 | 0.75 | PDK2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL31620240 | 0.75 | AOC3 (0.32) | — | |
| SCHEMBL25153128 | 0.73 | KDM4E (0.38) | — | |
| SCHEMBL30883856 | 0.73 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610258-A1 | FUSED PYRIDAZINE DERIVATIVE | Tenvie Therapeutics, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| CN-120152974-A | Cyclopyridazine derivatives | 天维生物制药有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2024090469-A1 | FUSED PYRIDAZINE DERIVATIVE | アステラス製薬株式会社 | 2024-05-02 | — | — | WO | disclosed |
| EP-2137162-B1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2018-08-01 | — | — | EP | disclosed |
| US-8536168-B2 | Benzyl and pyridinyl derivatives as modulators of the hedgehog signaling pathway | NOVARTIS AG (CH) | 2013-09-17 | — | — | US | disclosed |
| US-20100069368-A1 | Organic Compounds and Their Uses | NOVARTIS AG (CH) | 2010-03-18 | — | — | US | disclosed |
| EP-2137162-A1 | ORGANIC COMPOUNDS AND THEIR USES | Novartis Ag (CH) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008110611-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2008-09-18 | — | — | WO | disclosed |