Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361247 | 0.77 | AKT2 (0.41) | MAPK1AKT1AKT2PIM1GRM4 | |
| SCHEMBL20534083 | 0.73 | AKT2 (0.50) | MAPK1AKT1AKT2KDM4EALDH1A1 | |
| SCHEMBL14763854 | 0.71 | NPC1 (0.47) | MAPK1NPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL30557225 | 0.70 | ALDH1A1 (0.51) | MAPK1AKT1AKT2PIM1KDM4E | |
| SCHEMBL29590331 | 0.70 | AKT2 (0.46) | MAPK1AKT1AKT2PIM1GRM4 | |
| SCHEMBL23291933 | 0.70 | ALDH1A1 (0.51) | MAPK1AKT1AKT2PIM1KDM4E | |
| SCHEMBL15308510 | 0.70 | CYP2A6 (0.56) | MAPK1AKT1AKT2PIM1KDM4E | |
| SCHEMBL27090965 | 0.70 | AKT2 (0.46) | MAPK1AKT1AKT2PIM1GRM4 | |
| Hydrochloric Acid SCHEMBL30557160 | 0.69 | ALDH1A1 (0.50) | MAPK1AKT1AKT2PIM1KDM4E | |
| Hydrochloric Acid SCHEMBL32685351 | 0.69 | ALDH1A1 (0.50) | MAPK1AKT1AKT2PIM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097594-B2 | Macrolides and ketolides having antimicrobial activity | WOCKHARDT LTD. (IN) | 2012-01-17 | — | — | US | disclosed |