Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150403 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HPGDF2GLAPDE3B | |
| SCHEMBL20869368 | 0.81 | PDGFRB (0.46) | ALDH1A1HPGDF2GLAPDGFRB | |
| SCHEMBL3613071 | 0.80 | PDE3B (0.43) | ALDH1A1HPGDF2GLAPDE3B | |
| SCHEMBL3616022 | 0.80 | PDE3B (0.45) | ALDH1A1HPGDF2GLAPDE3B | |
| SCHEMBL27775618 | 0.80 | CYP3A4 (0.43) | ALDH1A1HPGDF2GLAPDE3B | |
| SCHEMBL3611213 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDF2GLAPDE3B | |
| SCHEMBL3615704 | 0.78 | ALDH1A1 (0.33) | ALDH1A1HPGDF2GLALMNA | |
| SCHEMBL31716011 | 0.78 | PDE3B (0.47) | ALDH1A1HPGDPDE3BPDE3APDGFRB | |
| SCHEMBL26681624 | 0.78 | PDE3B (0.47) | ALDH1A1HPGDPDE3BPDE3APDGFRB | |
| SCHEMBL27932593 | 0.77 | KMT2A (0.49) | ALDH1A1HPGDF2GLAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | ALDH1A1 350/4885HPGD 3828/4885F2 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.