Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 8/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006483 | 0.87 | CYP11B1 (0.59) | CYP11B1CYP11B2ALDH1A1MAPTGAA | |
| SCHEMBL28871720 | 0.87 | CYP11B1 (0.59) | CYP11B1CYP11B2ALDH1A1MAPTGAA | |
| SCHEMBL3609644 | 0.85 | GRM5 (0.59) | CYP11B1CYP11B2GAACYP3A4ALPL | |
| SCHEMBL22983039 | 0.84 | CYP11B1 (0.74) | CYP11B1CYP11B2ALDH1A1MAPTGAA | |
| SCHEMBL5361880 | 0.83 | HDAC1 (0.74) | ALDH1A1GAACYP3A4ALPLALPI | |
| SCHEMBL4466928 | 0.83 | ALDH1A1 (0.61) | CYP11B1CYP11B2ALDH1A1MAPTGAA | |
| SCHEMBL5361922 | 0.82 | GAA (0.77) | ALDH1A1GAACYP3A4ALPLALPI | |
| SCHEMBL13381471 | 0.80 | ALDH1A1 (0.70) | ALDH1A1GAACYP3A4ALPLALPI | |
| SCHEMBL13381489 | 0.80 | KMT2A (0.68) | ALDH1A1MAPTGAACYP3A4ALPL | |
| SCHEMBL5218533 | 0.80 | GAA (0.70) | CYP11B1CYP11B2ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029685-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029685-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | CHRNA3, CHRNA5, CHRNB3 | CYP11B1 1140/4885CYP11B2 977/4885ALDH1A1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.