Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL30701111 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL36149 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL9561748 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3275086 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL5473889 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL5987710 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL16671164 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL117285 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL5473892 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL4608211 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 34247 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079650-A | Method for preparing high-entropy ceramic matrix composite by reaction infiltration process | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079258-A | Nano-microstructure composite cathode for solid oxide electrolytic cell and preparation method | — | 2026-05-26 | — | — | CN | claimed |
| CN-121895671-B | Anti-cracking flame-retardant material for cables and preparation process thereof | JIANGSU HONGFENG CABLE GROUP Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116565173-B | High-rate coal-based hard carbon composite material and preparation method and application thereof | SHENZHEN JINPAI NEW ENERGY TECHNOLOGY Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121369665-B | Delicious peptide-based low-salt thick broad-bean sauce and production process thereof | Sichuan Dandan Pixian Bean Paste Group Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116236855-B | Air purifier filter element and preparation method and application thereof | Shenzhen Biaolang Environmental Protection New Material Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122079140-A | Low-temperature preparation technology for plasma-assisted hydrothermal synthesis of carbon nanotubes and cold cathode application | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076487-A | Carbon-nitrogen group modified inverse protein Dan Biji halogenated perovskite material, preparation method and application method | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076475-A | In-situ doped TiO with wide particle size range2Core-shell structure powder and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122078035-A | Network enhanced fluorescent composite fireproof glass and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-3983052-A | Process for rejuvenating automobile emission control catalysts | UNION OIL COMPANY OF CALIFORNIA (US) | 1976-09-28 | — | — | US | claimed |
| US-RE28957-E | Synthetic resin compositions and methods of utilizing the same | JOHNSON & JOHNSON (US) | 1976-09-07 | — | — | US | claimed |
| US-3976500-A | DICARBOXYLIC ACID SALTS, PERSULFATE, A UREA, AMMONIUM HYDROXIDE | ENTHONE, INCORPORATED (US) | 1976-08-24 | — | — | US | claimed |
| US-3973967-A | PRINTING PLATES, RESOLUTION | ITEK CORPORATION (US) | 1976-08-10 | — | — | US | claimed |
| US-3956236-A | NYLON, POLYESTERS, OR POLYURETHANES | ALLIED CHEMICAL CORPORATION (US) | 1976-05-11 | — | — | US | claimed |
| US-3951760-A | Bath for the electrodeposition of bright tin-cobalt alloy | SONY CORPORATION (JA) | 1976-04-20 | — | — | US | claimed |
| US-3944606-A | Process of producing alkali metal or ammonium citrates | JOH. A. BENCKISER GMBH (DT) | 1976-03-16 | — | — | US | claimed |
| US-3939047-A | Method for fabricating electrode structure for a semiconductor device having a shallow junction | NIPPON ELECTRIC CO., LTD. (JA) | 1976-02-17 | — | — | US | claimed |
| US-3931208-A | Process for the production of thiazolines-(3) | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-01-06 | — | — | US | claimed |
| US-3931085-A | POLYVALENT METAL COMPLEX | JOHNSON & JOHNSON (US) | 1976-01-06 | — | — | US | claimed |