Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL2037219 | 0.95 | TSHR (0.39) | PLA2G1BPLA2G2ATSHRTHRBSMN1; SMN2 | |
| Ether SCHEMBL7862995 | 0.89 | ALDH1A1 (0.38) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| Hexane SCHEMBL4267140 | 0.86 | TSHR (0.47) | TSHRTHRBSMN1; SMN2MEN1KMT2A | |
| Hexane SCHEMBL27706711 | 0.86 | TSHR (0.47) | PLA2G1BPLA2G2ATSHRTHRBSMN1; SMN2 | |
| Hexane SCHEMBL5415595 | 0.83 | TSHR (0.44) | TSHRTHRBSMN1; SMN2MEN1KMT2A | |
| Ether SCHEMBL324618 | 0.83 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1HSD17B10 | |
| Hexane SCHEMBL22319987 | 0.80 | SMN1; SMN2 (0.47) | PLA2G1BPLA2G2ATSHRTHRBSMN1; SMN2 | |
| Ether SCHEMBL7679488 | 0.80 | ALDH1A1 (0.43) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| Pentane SCHEMBL27609734 | 0.80 | TSHR (0.50) | TSHRTHRBSMN1; SMN2MEN1KMT2A | |
| Hexane SCHEMBL9422173 | 0.80 | TSHR (0.54) | PLA2G1BPLA2G2ATSHRTHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314110-B2 | Compounds for treating mental disorders, and preparation and uses thereof | LI YOUXIN (CN) | 2012-11-20 | — | — | US | disclosed |
| US-20100113482-A1 | Novel Compounds for Treating Mental Disorders, and Preparation and Uses Thereof | LI YOUXIN | 2010-05-06 | — | — | US | disclosed |
| EP-0639083-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1995-02-22 | — | — | EP | disclosed |
| WO-1993021957-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1993-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113482-A1 | Novel Compounds for Treating Mental Disorders, and Preparation and Uses Thereof | SLC18A2, SLC6A3, SLC6A2 | PLA2G1B 2410/4885PLA2G2A 2511/4885TSHR 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.