Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31746177 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30203909 | 0.91 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL2234634 | 0.91 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL16668827 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL31253545 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL2235175 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL29535036 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL3685625 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL31099218 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL8457636 | 0.81 | KDR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| EP-1511783-B1 | FLEXIBLE PROPYLENE COPOLYMER COMPOSITIONS HAVING A HIGH TRANSPARENCY | BASELL POLYOLEFINE GMBH (DE) | 2013-07-31 | — | — | EP | disclosed |
| EP-1730231-B1 | FLEXIBLE PROPYLENE COPOLYMER COMPOSITIONS HAVING A HIGH TRANSPARENCY | BASELL POLYOLEFINE GMBH (DE) | 2012-06-13 | — | — | EP | disclosed |
| EP-1871832-B1 | BIAXIALLY ORIENTED PROPYLENE POLYMER FILMS | BASELL POLIOLEFINE SRL (IT) | 2012-06-13 | — | — | EP | disclosed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | disclosed |
| US-7732530-B2 | Flexible propylene copolymer compositions having a high transparency | BASELL POLYOLEFINE GMBH (DE) | 2010-06-08 | — | — | US | disclosed |
| US-20090305069-A1 | Biaxially oriented propylene polymer films | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2009-12-10 | — | — | US | disclosed |
| US-7601777-B2 | Method for the production of an aqueous polymer dispersion | BASF AKTIENGESELLSCHAFT (DE) | 2009-10-13 | — | — | US | disclosed |
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| EP-1730231-A1 | FLEXIBLE PROPYLENE COPOLYMER COMPOSITIONS HAVING A HIGH TRANSPARENCY | Basell Polyolefine GmbH (DE) | 2006-12-13 | — | — | EP | disclosed |
| WO-2006111448-A1 | BIAXIALLY ORIENTED PROPYLENE POLYMER FILMS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2006-10-26 | — | — | WO | disclosed |
| US-20060167185-A1 | Propylene copolymer compositions having a good low-temperature impact toughness and a high transparency | BASELL POLYOLEFINE GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| US-20060058463-A1 | Flexible propylene copolymer compositions having a high transparency | BASELL POLYOLEFINE GMBH (DE) | 2006-03-16 | — | — | US | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |
| WO-2005090467-A1 | FLEXIBLE PROPYLENE COPOLYMER COMPOSITIONS HAVING A HIGH TRANSPARENCY | BASELL POLYOLEFINE GMBH (DE) | 2005-09-29 | — | — | WO | disclosed |
| US-20050176875-A1 | Method for the production of an aqueous polymer dispersion | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | US | disclosed |
| EP-1511803-A1 | PROPYLENE COPOLYMER COMPOSITIONS HAVING A GOOD LOW-TEMPERATURE IMPACT TOUGHNESS AND A HIGH TRANSPARENCY | Basell Polyolefine GmbH (DE) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003106553-A1 | PROPYLENE COPOLYMER COMPOSITIONS HAVING A GOOD LOW-TEMPERATURE IMPACT TOUGHNESS AND A HIGH TRANSPARENCY | BASELL POLYOLEFINE GMBH (DE) | 2003-12-24 | — | — | WO | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |