SCHEMBL361798

SCHEMBL361798

O=C(O)C(=O)CCC(=O)C(=O)O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 2/20 0.79
EGLN1 Q9GZT9 2/20 0.79
MAPK1 P28482 1/20 0.79
SLC13A3 Q8WWT9 1/20 0.79
LMNA P02545 3/20 0.43
ALKBH5 Q6P6C2 1/20 0.43
SUCNR1 Q9BXA5 1/20 0.43
SLC22A6 Q4U2R8 1/20 0.38
HAO1 Q9UJM8 1/20 0.36
TSHR P16473 2/20 0.35
CASP1 P29466 1/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
LDHA P00338 2/20 0.33
LDHB P07195 1/20 0.33
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27857415 0.96 OR51E2 (0.73) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL3776640 0.89 EGLN1 (1.00) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL30208560 0.89 EGLN1 (1.00) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL30029036 0.89 EGLN1 (1.00) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL932116 0.89 EGLN1 (1.00) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL29783374 0.89 EGLN1 (1.00) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL7400 0.89 EGLN1 (1.00) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL17127347 0.89 EGLN1 (1.00) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL1242830 0.86 EGLN1 (0.93) OR51E2EGLN1MAPK1SLC13A3LMNA
Alpha-Ketoglutaric Acid SCHEMBL3184813 0.86 EGLN1 (0.93) OR51E2EGLN1MAPK1SLC13A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN claimed
CN-115819238-A Low-migration hindered phenol antioxidant compound, preparation method and composition 优禘股份有限公司 2023-03-21 CN disclosed
WO-2022271183-A1 SELF-ASSEMBLING AMPHPHLIC POLYMERS AS ANTI-COVID-19 AGENTS ALLEXCEL INC. (US) 2022-12-29 WO disclosed
WO-2022272181-A1 SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-COVID-19 AGENTS ALLEXCEL INC. (US) 2022-12-29 WO disclosed
CN-113201539-B Polynucleotides having promoter activity and use thereof for producing target compounds 中国科学院天津工业生物技术研究所 2022-09-06 CN disclosed
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN disclosed
CN-113443991-A Low-migration hindered phenol antioxidant compound, preparation method and composition 优禘股份有限公司 2021-09-28 CN disclosed
CN-109180843-A The non-phthalic acid ester compound as electron donor for polyolefin catalyst 美国台塑公司 2019-01-11 CN disclosed
CN-105339085-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2018-06-26 CN disclosed
US-20100331191-A1 SURFACTANT COMPOUNDS CRODA INTERNATIONAL PLC (GB) 2010-12-30 US disclosed
US-20100144902-A1 BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) 2010-06-10 US disclosed
EP-2177236-A1 A METHOD FOR THE FORMATION OF A RAPID-GELLING BIOCOMPATIBLE HYDROGEL AND THE PREPARATION OF A SPRAYING AGENT Bioregen Biomedical (Changzhou) Co., Ltd. (CN) 2010-04-21 EP disclosed
EP-2089353-A2 SURFACTANT COMPOUNDS CRODA INTERNATIONAL plc (GB) 2009-08-19 EP disclosed
WO-2008059234-A2 SURFACTANT COMPOUNDS CRODA INTERNATIONAL PLC (GB) 2008-05-22 WO disclosed
US-5554744-A Method for loading solid supports for nucleic acid synthesis HYBRIDON, INC. (US) 1996-09-10 US disclosed
WO-1996009314-A2 METHOD FOR LOADING SOLID SUPPORTS FOR NUCLEIC ACID SYNTHESIS HYBRIDON, INC. (US) 1996-03-28 WO disclosed
EP-0408255-B1 Thermoplastic resin composition SUMITOMO CHEMICAL CO (JP) 1995-05-17 EP disclosed
US-5182151-A Polyphenylene ether, propylene graft polymer, rubber, molding material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-01-26 US disclosed
EP-0408255-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144902-A1 BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY CSTB, CAPG, F12 OR51E2 1454/4885EGLN1 662/4885MAPK1 3577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.