Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | LIG1 | P18858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395315 | 0.86 | HPGD (0.43) | TSHRMAPK1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL3435213 | 0.84 | ADRA2A (0.46) | TSHRMAPK1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL17329279 | 0.84 | ADRA2A (0.46) | TSHRMAPK1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL19759485 | 0.82 | ALDH1A1 (0.50) | TSHRMAPK1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2555115 | 0.81 | ALDH1A1 (0.49) | TSHRMAPK1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7113700 | 0.81 | LIG1 (0.49) | TSHRMAPK1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL5134014 | 0.80 | HPGD (0.46) | TSHRMAPK1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL16112318 | 0.80 | FFAR1 (0.48) | TSHRMAPK1HPGDHSD17B10ADRA2A | |
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.80 | HPGD (0.60) | TSHRMAPK1HPGDHSD17B10ALDH1A1 | |
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.80 | HPGD (0.60) | TSHRMAPK1HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311474-B | Synthesis method of 3-alkynyl pyridine compound | 河南师范大学 | 2017-01-11 | — | — | CN | disclosed |
| CN-104311474-A | Synthesis method of 3-alkynyl pyridine compound | UNIV HENAN NORMAL | 2015-01-28 | — | — | CN | disclosed |
| EP-2593461-A1 | COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | Bristol-Myers Squibb Company (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012009309-A1 | COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-01-19 | — | — | WO | disclosed |
| US-6008401-A | CONDENSATION REACTION BETWEEN 4-HALO OR NITRO SUBSTITUTED BENZONITRILE DERIVATIVE AND OTICALLY ACTIVE ALCOHOL PRODUCES AN OPTICALLY ACTIVE ALKOXYBENZONITRILE DERIVATIVE | NIPPON OIL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| US-5380654-A | Process for the preparation of epoxides of means of microorganisms | JAPAN ENERGY CORPORATION (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5376539-A | Aerobic incubation of allyl phenyl ether with arthrobacter, brevibacterium, corynebacterium, pseudomonas or rhodococcus yields glycidyl phenyl ether | NIPPON MINING CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0166527-B1 | A PROCESS FOR THE PREPARATION OF EPOXIDES BY MEANS OF MICROORGANISMS | NIPPON MINING COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0411787-A2 | Microbiological production of 2,3-epoxypropyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-06 | — | — | EP | disclosed |
| EP-0166527-A2 | A process for the preparation of epoxides by means of microorganisms | NIPPON MINING COMPANY LIMITED (JP) | 1986-01-02 | — | — | EP | disclosed |